%0 Journal Article
%T Matrix metalloproteinases (MMPs) and trophoblast invasion
Matrix metalloproteinases (MMPs) and trophoblast invasion
%A Jing Li
%A Tianfu Zhao
%A Enkui Duan
%A
LIJing
%A ZHAOTianfu
%A DUANEnkui
%J 科学通报(英文版)
%D 2005
%I
%X MMPs and their natural tissue inhibitors TIMPs are crucial in coordinated breakdown and remodel- ing of the extracellular matrix (ECM) in physiological and pathological situations. Placentation is a key event of pregnancy in which MMPs/TIMPs system plays important roles in regulating the extravillus cytotrophoblast (EVTs) invasion. This paper focuses on expression patterns and regulatory mechanisms of MMPs/TIMPs family members during the process of placentation. Their implications in curing pregnancy-related diseases are also discussed.
%K MMPs
%K TIMPs
%K placenta
%K trophoblast invasion
%K extracel- lular matrix (ECM)
MMPs
%K 细胞外矩阵
%K 组织抑制剂
%K 胚胎入侵
%K 胎盘
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=74B22DA79DB93373AEB2F4FA7CE74B48&yid=2DD7160C83D0ACED&vid=771152D1ADC1C0EB&iid=59906B3B2830C2C5&sid=827D3389B7A27A64&eid=778972EBEFCE1267&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=36