%0 Journal Article
%T Sequence analysis on biological active peptides using electrospray ionization-Fourier transform ion cyclotron resonance mass spectrometer
Sequence analysis on biological active peptides using electrospray ionizationFourier transform ion cyclotron resonance mass spectrometer
%A Chen Hui
%A Xu Jiaxi
%A Xin Bin
%A He Meiyu
%A
CHENHui
%A XUJiaxi
%A XINBin
%A HEMeiyu
%J 科学通报(英文版)
%D 2005
%I
%X This paper describes experience with the sequencing of synthetic segment peptides of gp41 which are used in trimeric peptides as potential peptide-based vaccines and as inhibitors to mimic the fusion state of gp41 in HIV infection using ESI/CID-FT-ICR MS. All b and y′’ series ions are found in the CID spectra and the mass difference between the calculated and observed results is very slight. FT-ICR MS again shows its power in peptide sequencing, successfully helping us obtain the sequence of an unknown peptide.
%K peptide
%K ESI
%K FT-ICR MS
%K SORI-CID
缩氨酸
%K 分子序列
%K 生物学
%K 回旋加速器
%K 电离作用
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=E9B3CE0D2DA8147DB24E176F88E068D9&yid=2DD7160C83D0ACED&vid=771152D1ADC1C0EB&iid=9CF7A0430CBB2DFD&sid=970314C3B74F6C4D&eid=E002FF26604EFFAB&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=24