%0 Journal Article
%T Chemical Sensors ¨C from Molecules, Complex Mixtures to Cells ¨C Supramolecular Imprinting Strategies
%A Franz L. Dickert
%A Peter A. Lieberzeit
%A Oliver Hayden
%A Sylvia Gazda-Miarecka
%A Konstantin Halikias
%A Karl J¨¹rgen Mann
%A Christian Palfinger
%J Sensors
%D 2003
%I MDPI AG
%R 10.3390/s30900381
%X Methods of modern chemistry are a powerful tool in generating functional materials suitable as chemically sensitive layers to be combined with a variety of transducer principles. Molecular pits in polymers are formed by molecular imprinting, by suitable double-imprinting e.g. PAHs can be detected down to the sub-¦Ìg/l level. The resulting selectivity patterns depend both on the polymerization temperature and the template/mononomer composition. Organic contaminants in water can be either directly assessed in liquid phase or separated from the matrix by a porous Teflon membrane. Thus the detection limits can be reduced to the ppm-level due to the a much lower noise level in gaseous phase. Even complex processes such as engine oil degradation can be followed by suitably imprinted polymers. Pits on the nm- to ¦Ìm scale are reached by surface templating polymers with microorganisms. The resulting layers show reversible, antibody-like interactions and thus are optimal sensor layers. The successful on-line detection of tobacco mosaic viruses (TMV) can be achieved by these surface imprinted layers.
%K Molecular imprinting
%K self-assembly
%K PAH detection
%K solvent detection
%K engine oil degradation measurements
%K virus detection
%U http://www.mdpi.com/1424-8220/3/9/381