%0 Journal Article
%T pH effect of · OH radical induced oxidation of phosphorylmethionine in aqueous solution<br>pH effect of· OH radical induced oxidation of phosphoryl- methionine in aqueous solution
%A Gaosheng Chu
%A Side Yao
%A Zhicheng Zhang
%A Manwei Zhang
%A Wenfeng Wang
%A <br>
%J 科学通报(英文版)
%D 1997
%I 
%X Conclusion The results of pulse radiolytical research on the · OH radical-induced oxidation of NDM in aqueous solution demonstrate that pH value has a great influence on the radiolytical mechanism of NDM. At low pH value, the product is mainly stabilization of the oxidizing sulfur centre in the three-electron-bonded cation radical NDM2 ·+ S]; with the increase of pH value, NDM2 ·+ S] gradually decays to become the reducing α-amino radical which was verified by the chemical method and whose yield was also calculated. Compared with Met2 ·+ S] produced by the · OH radical-induced oxidation in aqueous solution 1], the stability of NDM2·+ S] increases and the yield of α-amino radical decreases. This suggests that the introduction of phosphoryl group has a coordinating effect on the radioprotection of methionine to biological systems, and provides the essentially theoretical foundation for the thorough clarification of the reversible phosphorylation of proteins.
%K pulse radiolysis
%K NDM
%K α
%K -amino radical
%K pH effect<br>
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=01BA20E8BA813E1908F3698710BBFEFEE816345F465FEBA5&cid=96E6E851B5104576C2DD9FC1FBCB69EF&jid=DD6615BC9D2CFCE0B6F945E8D5314523&aid=F352CE78834A536605713C3DE7253983&yid=5370399DC954B911&vid=ECE8E54D6034F642&iid=E158A972A605785F&sid=D0182A31A5EB14BA&eid=D0182A31A5EB14BA&journal_id=1001-6538&journal_name=科学通报(英文版)&referenced_num=0&reference_num=12