%0 Journal Article
%T Vitamin A Metabolism and Adipose Tissue Biology
%A Simone K. Frey
%A Silke Vogel
%J Nutrients
%D 2011
%I MDPI AG
%R 10.3390/nu3010027
%X In recent years, the importance of vitamin A in adipose tissue biology, obesity and type II diabetes has become apparent. This review focuses on recent developments within the area of vitamin A and adipose tissue biology. Adipose tissue has an active vitamin A metabolism as it not only stores vitamin A but retinol is also converted to its active metabolite retinoic acid. Several mouse models point to a relationship between vitamin A metabolism and the development of adiposity. Similarly, in vitro studies provide new molecular mechanisms for the function of different forms of vitamin A and retinol- or retinoic acid-binding proteins in adipose tissue.
%K retinol
%K retinoic acid
%K adipose tissue
%K cellular retinol-binding protein
%K beta-carotene
%K adipogenesis
%U http://www.mdpi.com/2072-6643/3/1/27