%0 Journal Article
%T Thiadiazines, N,N-Heterocycles of Biological Relevance
%A Hortensia Rodr¨ªguez
%A Margarita Su¨¢rez
%A Fernando Albericio
%J Molecules
%D 2012
%I MDPI AG
%R 10.3390/molecules17077612
%X The 3,5-disubstituted tetrahydro-2H-1,3,5-thiadiazine-2-thione scaffold has found many applications in recent years. This review is aimed at highlighting the most important aspects of these compounds: Synthesis, spectroscopic characterization and biological activities. How the chemical nature of N-substituents influences the overall activity and cytotoxicity profile will also be discussed.
%K heterocycles
%K thiadiazines
%K synthesis and biological activity
%U http://www.mdpi.com/1420-3049/17/7/7612