%0 Journal Article
%T Synthesis and Fungicidal Activity of Novel 2,3-Disubstituted-1,3-benzoxazines
%A Zilong Tang
%A Zhonghua Zhu
%A Zanwen Xia
%A Hanwen Liu
%A Jinwen Chen
%A Wenjing Xiao
%A Xiaoming Ou
%J Molecules
%D 2012
%I MDPI AG
%R 10.3390/molecules17078174
%X A series of new 2,3-disubstituted-3,4-dihydro-2H-1,3-benzoxazines were prepared in moderate to excellent yields by aza-acetalizations of aromatic aldehydes with 2-(N-substituted aminomethyl)phenols in the presence of TMSCl. Their structures were confirmed by IR, 1H-NMR, 13C-NMR, MS and elemental analysis. The fungicidal activities of the target compounds were preliminarily evaluated, and some compounds exhibited good activity against Rhizoctonia solani.
%K 2
%K 3-disubstituted-1
%K 3-benzoxazine
%K synthesis
%K chlorotrimethylsilane
%K fungicidal activity
%U http://www.mdpi.com/1420-3049/17/7/8174