%0 Journal Article
%T Synthesis, Structure and Antifungal Activity of New 3-[(5-Aryl-1,3,4-oxadiazol-2-yl)methyl]benzo[d]thiazol-2(3H)-ones
%A Jian-Quan Weng
%A Xing-Hai Liu
%A Hua Huang
%A Cheng-Xia Tan
%A Jie Chen
%J Molecules
%D 2012
%I MDPI AG
%R 10.3390/molecules17010989
%X A series of new 3-[(5-aryl-1,3,4-oxadiazol-2-yl)methy])benzo[d]thiazol-2(3H)-ones were synthesized by reaction of (5-substituted-2-oxobenzothiazolin-3-yl)-acetohydrazide with various aromatic acids in POCl3 under reflux conditions. The structures of the title compounds were confirmed by 1H-NMR, 13C-NMR, IR, MS and elemental analysis. Furthermore, the structure of compound 4i was determined by single-crystal X-ray diffraction. The preliminary bioassy results indicated that some of them showed moderate inhibition activity against Colletotrichum orbiculare, Botrytis cinerea and Rhizoctonia solani.
%K 3-[(5-aryl-1
%K 3
%K 4-oxadiazol-2-yl)methyl]benzo[d]thiazol-2(3H)-ones
%K synthesis
%K crystal structure
%K antifungal activity
%U http://www.mdpi.com/1420-3049/17/1/989