%0 Journal Article
%T Inhibitory effects of Phellinus baumii polysaccharide on the proliferation and invasion of HepG2 cell<br>鲍姆木层孔菌多糖对HepG2细胞增殖及侵袭相关能力的抑制作用
%A WANG Gui-Bin
%A DONG Lu-Lu
%A JI Yuan-Yuan
%A XIANG Wen-Hua
%A ZHAO Min
%A <br>王贵宾
%A 董露璐
%A 姬媛媛
%A 相文华
%A 赵敏
%J 菌物学报
%D 2011
%I 
%X The inhibitory effects of Phellinus baumii polysaccharide PLP60-B1 on the proliferation and invasion of HepG2 cancer cells were investigated. The homogeneous Phellinus baumii polysaccharide PLP60-B1 having promoting effects on lymphocyte proliferation was obtained by ethanol precipitation and purified by DEAE-Sepharose F.F. and Sephacryl S-200. MTT assay and flow cytometry showed that PLP60-B1 inhibited cell proliferation as well as colony formation of HepG2 cells through the S-phase cell cycle arrest, and the homogeneous polysaccharide also demonstrated the remarkably inhibition of adhesion and invasion in HepG2 cells.
%K macrofungi
%K antitumor
%K cell cycle
%K invasiveness<br>大型真菌，抗肿瘤，细胞周期，侵袭
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=CA9F815FCB0F62294C4266BB6F902ACB&aid=F4E66C3FE2D6886090C3B4392D016226&yid=9377ED8094509821&vid=340AC2BF8E7AB4FD&iid=0B39A22176CE99FB&sid=334C61CAF4C8EF4E&eid=E39A3F4E3A67639B&journal_id=1672-6472&journal_name=菌物学报&referenced_num=0&reference_num=0