%0 Journal Article
%T Synthesis of Quinoxaline 1,4-di-N-Oxide Analogues and Crystal Structure of 2-Carbomethoxy-3-hydroxyquinoxaline-di-N-oxide
%A Yingjun Xu
%A Fanhong Wu
%A Zhiyi Yao
%A Minmin Zhang
%A Sheng Jiang
%J Molecules
%D 2011
%I MDPI AG
%R 10.3390/molecules16086894
%X A series of quinoxaline 1,4-di-N-oxide analogues were prepared from benzofurazan N-oxide derivatives and ¦Â-diketone ester compounds by the improved Beirut reaction. The structures of the target products were characterized by NMR, MS, IR and elemental analysis measurements, and that of 2-carbomethoxy-3-hydroxyquinoxaline- di-N-oxide was further confirmed by single-crystal X-ray diffraction. Its crystal structure belongs to the monoclinic system, space group C2/c with a = 14.4320 (12) £¿, b = 10.7514 (9) £¿, c = 13.2728 (11) £¿, V = 1958.5 (3) £¿ 3, Z = 8. The X-ray crystallographic analysis reveals that quinoxaline 1,4-di-N-oxide displays acyloin-endiol tautomerism.
%K quinoxaline 1
%K 4-di-N-oxide
%K Beirut reaction
%K acyloin-endiol tautomerism
%U http://www.mdpi.com/1420-3049/16/8/6894