%0 Journal Article
%T The effects of Amanita exitialis toxin on the cure of mouse skin papillomas chemically induced by DMBA/ croton oil
致命鹅膏菌毒素对DMBA/巴豆油诱导小鼠皮肤肿瘤的治疗作用
%A SHU Chang
%A TAO Wen-Yi
%A ZHOU Tu
%A
舒畅
%A 陶文沂
%A 周荼
%J 菌物学报
%D 2007
%I
%X Inhibition effect of the toxin in Amanita exitialis on mouse skin papillomas under safe dose and the drug safety was evaluated primarily.The mouse skin papilloma model was established by 7,12-dimethylbenz(a) anthraene(DMBA)/croton oil induction,which was a classical two-stage cancer model.The inhibition effect of Amanita exitialis toxin was observed and evaluated under different doses.By means of analysis of amino-hexose in serum,the hepatic celt damage induced by toxin was determined.The result showed that Amanita exitialis toxin in tow dose can cure skin tumor in dose-dependent manner,and no harmful effect for hepatic cell.It was concluded that Amanita exitialis toxin can cure skin cancer.
%K Amanita exitialis
%K skin papilloma
%K cure
%K amino-hexose
致命鹅膏
%K 皮肤肿瘤
%K 治疗
%K 氨基己糖
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=CA9F815FCB0F62294C4266BB6F902ACB&aid=18726727449183AA3F6F4C3BB83AD09F&yid=A732AF04DDA03BB3&vid=96C778EE049EE47D&iid=0B39A22176CE99FB&sid=03E56C113B4E5A88&eid=334C61CAF4C8EF4E&journal_id=1672-6472&journal_name=菌物学报&referenced_num=0&reference_num=21