%0 Journal Article
%T One-Pot Synthesis of 2,3,4-Triarylquinolines via Suzuki-Miyaura Cross-Coupling of 2-Aryl-4-chloro-3-iodoquinolines with Arylboronic Acids
%A Malose Jack Mphahlele
%A Mamasegare Mabel Mphahlele
%J Molecules
%D 2010
%I MDPI AG
%R 10.3390/molecules15107423
%X Palladium¨Ccatalyzed Suzuki cross-coupling of 2-aryl-4-chloro-3-iodoquinolines with excess arylboronic acids (2.5 equiv.) in the presence of tricyclohexylphosphine afforded the 2,3,4-triarylquinolines in one-pot operation. The incipient 2,3-diaryl-4-chloroquinolines were also prepared and transformed to the primary 4-amino-2,3-diarylquinolines and 2,3-diarylquinolin-4(1H)-ones.
%K 2-aryl-4-chloro-3-iodoquinolines
%K Suzuki-Miyaura cross-coupling
%K 2
%K 3-diaryl-4-chloroquinolines
%K 2
%K 3
%K 4-triarylquinolines
%U http://www.mdpi.com/1420-3049/15/10/7423