%0 Journal Article %T Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models %A Karel £¿mejkal %A Tereza £¿lapetov¨¢ %A Pavel Krmen£¿¨ªk %A Renata Kub¨ªnov¨¢ %A Pavel Suchy %A Stefano Dall¡äAcqua %A Gabbriella Innocenti %A J¨¢n Van£¿o %A Karol¨ªna Kalvarov¨¢ %A Margita Dvorsk¨¢ %A Ji£¿¨ª Slanina %A Eva Kram¨¢£¿ov¨¢ %A Jan Musel¨ªk %A Milan £¿emli£¿ka %J Molecules %D 2010 %I MDPI AG %R 10.3390/molecules15031223 %X The in vitro antiradical activity of Schisandra chinensis lignans was investigated using DPPH, ABTS+, Fenton reaction inhibition and tyrosine-nitration inhibition assays, as were the in vivo antidiabetic activities of selected lignans in an animal model of alloxan-induced diabetes. Different degrees of antiradical activity were found, depending upon the structural parameters of the tested compounds. Unfortunately, the compounds showed no antidiabetic activity in concentration range tested. %K Schisandra chinensis %K dibenzocyclooctadiene lignans %K antiradical %K diabetes mellitus %U http://www.mdpi.com/1420-3049/15/3/1223