%0 Journal Article
%T Evaluation of the Antiradical Activity of Schisandra Chinensis Lignans Using Different Experimental Models
%A Karel £¿mejkal
%A Tereza £¿lapetov¨¢
%A Pavel Krmen£¿¨ªk
%A Renata Kub¨ªnov¨¢
%A Pavel Suchy
%A Stefano Dall¡äAcqua
%A Gabbriella Innocenti
%A J¨¢n Van£¿o
%A Karol¨ªna Kalvarov¨¢
%A Margita Dvorsk¨¢
%A Ji£¿¨ª Slanina
%A Eva Kram¨¢£¿ov¨¢
%A Jan Musel¨ªk
%A Milan £¿emli£¿ka
%J Molecules
%D 2010
%I MDPI AG
%R 10.3390/molecules15031223
%X The in vitro antiradical activity of Schisandra chinensis lignans was investigated using DPPH, ABTS+, Fenton reaction inhibition and tyrosine-nitration inhibition assays, as were the in vivo antidiabetic activities of selected lignans in an animal model of alloxan-induced diabetes. Different degrees of antiradical activity were found, depending upon the structural parameters of the tested compounds. Unfortunately, the compounds showed no antidiabetic activity in concentration range tested.
%K Schisandra chinensis
%K dibenzocyclooctadiene lignans
%K antiradical
%K diabetes mellitus
%U http://www.mdpi.com/1420-3049/15/3/1223