%0 Journal Article
%T Synthesis and Effect on Human HepG2 Cells of 1,2-bis- (2-Methylallyl)disulfane
%A Chunxiao Ji
%A Fenglian Ren
%A Jun Dai
%A Ming Xu
%J Molecules
%D 2010
%I MDPI AG
%R 10.3390/molecules15053634
%X 1,2-bis(2-methylallyl)disulfane was synthesized from sodium sulfide and 3-chloro-2-methylpropylene. The structure of the target product was confirmed by GC-MS, 1H-NMR and elemental analysis. Cell viability assay, flow-cytometric analysis and protein expression results showed that 1,2-bis(2-methylallyl)disulfane could significantly inhibit the proliferation, and induce the apoptosis of human HepG2 cells.
%K 1
%K 2-bis(2-methylallyl)disulfane
%K identification
%K apoptosis
%U http://www.mdpi.com/1420-3049/15/5/3634