%0 Journal Article %T Synthesis of syn-¦Ã-Amino-¦Â-hydroxyphosphonates by Reduction of ¦Â-Ketophosphonates Derived from L-Proline and L-Serine %A Mario Ord¨®£¿ez %A Selene Lagunas-Rivera %A Emanuel Hern¨¢ndez-N¨²£¿ez %A Victoria Labastida-Galv¨¢n %J Molecules %D 2010 %I MDPI AG %R 10.3390/molecules15031291 %X The reduction of ¦Ã-N-benzylamino-¦Â-ketophosphonates 6 and 10, readily available from L-proline and L-serine, respectively, can be carried out in high diastereoselectivity with catecholborane (CB) in THF at -78 oC to produce the syn-¦Ã-N-benzylamino-¦Â-hydroxyphosphonates 11 and 13 as a single detectable diastereoisomer, under non-chelation or Felkin-Anh model control. %K ¦Â-ketophosphonates %K diastereoselective reduction %K ¦Ã-amino-¦Â-hydroxy-phosphonates %U http://www.mdpi.com/1420-3049/15/3/1291