%0 Journal Article
%T Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis
%A Min Xu
%A Marc Litaudon
%A Sabrina Krief
%A Marie-Th¨¦r¨¨se Martin
%A John Kasenene
%A Bernard Kiremire
%A Vincent Dumontet
%A Fran£¿oise Gu¨¦ritte
%J Molecules
%D 2009
%I MDPI AG
%R 10.3390/molecules14103844
%X One new drimane-type sesquiterpenoid, named ugandenial A (1), was isolated from the ethyl acetate extract of the bark of Warburgia ugandensis (Canellaceae) together with eight known drimane-type sesquiterpenoids: 11¦Á-hydroxycinnamosmolide (2), warburganal (3), polygodial (4), mukaadial (5), dendocarbin A (6), 9¦Á-hydroxycinnamolide (7), dendocarbin L (8) and dendocarbin M (9). Their structures were established by detailed spectroscopic analysis. In addition a keto-enol equilibrium was demonstrated for compound 1 through a detailed NMR analysis run in CD2Cl2 at 190 K. Cytotoxicity of the isolated compounds against KB cells was evaluated.
%K Warburgia ugandensis
%K drimane-type sesquiterpenoid
%K ugandenial
%K cytotoxicity
%U http://www.mdpi.com/1420-3049/14/10/3844