%0 Journal Article
%T Synthesis and Characterization of N-(Arylcarbamothioyl)-cyclohexanecarboxamide Derivatives: The Crystal Structure of N-(Naphthalen-1-ylcarbamothioyl)cyclohexanecarboxamide
%A Cemal Koray £¿zer
%A Hakan Arslan
%A Don VanDerveer
%A Nevzat K¨¹lc¨¹
%J Molecules
%D 2009
%I MDPI AG
%R 10.3390/molecules14020655
%X A number of N-(arylcarbamothioyl)cyclohexanecarboxamide derivatives (aryl substituents: phenyl, 2-chlorophenyl, 3-chlorophenyl, 4-chlorophenyl, o-tolyl, p-tolyl, 3-methoxyphenyl, 4-methoxyphenyl and naphthalen-1yl) have been synthesized. The compounds obtained were characterized by elemental analyses, IR spectroscopy and 1H-NMR spectroscopy. N-(naphthalen-1-ylcarbamothioyl)cyclohexanecarboxamide, H2L9, was also characterized by a single crystal X-ray diffraction study. This compound, C18H20N2OS, crystallizes in the triclinic space group P¨©, with Z = 2, and unit cell parameters a = 6.9921(14) £¿, b = 11.002(2) £¿, c = 12.381(3) £¿, ¦Á = 113.28(3)¡ã, b = 99.38(3)¡ã, and g = 101.85(3)¡ã. The cyclohexane ring adopts a chair conformation. The molecular conformation of the compound is stabilized by an intramolecular (N2-H2£¿£¿£¿O1) hydrogen bond which forms a pseudo-six-membered ring.
%K Synthesis
%K Cyclohexane
%K Thiourea
%K Single crystal structure
%K Pseudo-six-membered ring
%U http://www.mdpi.com/1420-3049/14/2/655