%0 Journal Article
%T Mechanochemical Solvent-Free and Catalyst-Free One-Pot Synthesis of Pyrano[2,3-d]Pyrimidine-2,4(1H,3H)-Diones with Quantitative Yields
%A Sara Mashkouri
%A M. Reza Naimi-Jamal
%J Molecules
%D 2009
%I MDPI AG
%R 10.3390/molecules14010474
%X Solvent-free synthesis of pyrano[2,3-d]pyrimidine-2,4(1H,3H)-diones by ball-milling and without any catalyst is described. This method provides several advantages such as being environmentally friendly, using a simple workup procedure, and affording high yields.
%K Solvent-free reaction
%K Barbituric acid
%K Pyrimidinediones
%K Heterocyclic compounds
%K Ball-milling
%U http://www.mdpi.com/1420-3049/14/1/474