%0 Journal Article
%T New Triterpene Glucosides from the Roots of Rosa laevigata Michx
%A Jing-Quan Yuan
%A Xin-Zhou Yang
%A Jian-Hua Miao
%A Chun-Ping Tang
%A Chang-Qiang Ke
%A Ji-Bao Zhang
%A Xiao-Jun Ma
%A Yang Ye
%J Molecules
%D 2008
%I MDPI AG
%R 10.3390/molecules13092229
%X Two new ursane-type triterpene glucosides, 2¦Á,3¦Á,24-trihydroxyurs-12,18-dien-28-oic acid ¦Â-D-glucopyranosyl ester (1) and 2¦Á,3¦Á,23-trihydroxyurs-12,19(29)-dien-28-oic acid ¦Â-D-glucopyranosyl ester (2), were isolated from the roots of Rosa laevigata, together with three known compounds: 2¦Á,3¦Â,19¦Á-trihydroxyurs-12-en-28-oic acid ¦Â-Dglucopyranosyl ester (3), 2¦Á,3¦Á,19¦Á-trihydroxyurs-12-en-28-oic acid ¦Â-D-glucopyranosyl ester (4) and 2¦Á,3¦Â,19¦Á,23-tetrahydroxyurs-12-en-28-oic acid ¦Â-D-glucopyranosyl ester (5). The structures of new compounds were established on the basis of detailed 1D and 2D NMR spectroscopic analyses. Compounds 2 and 5 exhibited modest in vitro antifungal activities against Candida albicans and C. krusei.
%K Ursane-type triterpene glucosides
%K Rosa laevigata
%K Antifungal activity
%U http://www.mdpi.com/1420-3049/13/9/2229