%0 Journal Article
%T Antifouling Metabolites from the Mangrove Plant Ceriops tagal
%A Jun De Chen
%A Dan Qin Feng
%A Zhi Wei Yang
%A Zhan Chang Wang
%A Yan Qiu
%A Yi Ming Lin
%J Molecules
%D 2008
%I MDPI AG
%R 10.3390/molecules13020212
%X The new diterpene methoxy-ent-8(14)-pimarenely-15-one (1) and three knownmetabolites: ent-8(14)-pimarene-15R,16-diol (2), stigmasterol (3) and ¦Â-sitosterol (4), wereisolated from the roots of the mangrove plant Ceriops tagal. Their structures and relativestereochemistry were elucidated by means of extensive NMR, IR and MS analysis.Compounds 1, 2, 3 and 4 exhibited significant antifouling activities against cyprid larvaeof the barnacle Balanus albicostatus Pilsbry, with EC50 values of 0.32 ¡À 0.01, 0.04 ¡À 0.00,4.05 ¡À 0.15 and 18.47 ¡À 0.40 ¦Ìg/cm2, respectively, whereas their toxicities towards cypridswere very low, with LC50 values all above 10 ¦Ìg/cm2.
%K Diterpenes
%K antifouling activity
%K barnacle
%K Ceriops tagal
%U http://www.mdpi.com/1420-3049/13/2/212