%0 Journal Article
%T Synthetic Approaches to Heterocyclic Ligands for Gd-Based MRI Contrast Agents
%A Elena P¨¦rez-Mayoral
%A Jordi Soler-Padr¨®s
%A Viviana Negri
%A Sebasti¨˘n Cerd¨˘n
%A Paloma Ballesteros
%J Molecules
%D 2007
%I MDPI AG
%R 10.3390/12081771
%X Magnetic Resonance Imaging (MRI) methods are currently used in the clinic for the non invasive detection and characterization of a wide variety of pathologies. Increases in the diagnostic efficiency of MRI have been helped by both the design of dedicated MR sequences revealing specific aspects of the pathology and by the development of more sensitive and selective Contrast Agents (CAs), capable of more precisely delineating the borderline regions. In the present review we focus on the synthetic strategies used to obtain MRI CAs containing heterocyclic rings.
%K Lanthanide Complexes
%K Contrast Agents
%K Heterocyclic Ligands
%K MR Imaging
%U http://www.mdpi.com/1420-3049/12/8/1771