%0 Journal Article
%T Synthesis of Novel N-Sulfonyl Monocyclic ¦Â-Lactams as Potential Antibacterial Agents
%A Aliasghar Jarrahpour
%A Maaroof Zarei
%J Molecules
%D 2006
%I MDPI AG
%R 10.3390/11010049
%X New cis monocyclic ¦Â-lactams were synthesized by [2+2] Staudinger cycloaddition reactions of the imine (3,4-dimethoxybenzylidene)-(4-methoxyphenyl)- amine and ketenes derived from different acyl chlorides and Et3N. These monocyclic ¦Â-lactams were then cleaved by ceric ammonium nitrate (CAN) to give NH-monocyclic ¦Â-lactams, which in turn were converted to N-sulfonyl monocyclic ¦Â-lactams by treatment with four different sulfonyl chlorides in the presence of Et3N and 4,4-dimethyl- aminopyridine (DMAP).
%K 2-Azetidinones
%K N-Sulfonyl ¦Â-lactams
%K Ketene
%K Imine
%K CAN
%K DMAP
%U http://www.mdpi.com/1420-3049/11/1/49