%0 Journal Article
%T Synthesis and Antifungal Bioactivities of 3-Alkylquinazolin- 4-one Derivatives
%A Guiping Ouyang
%A Peiquan Zhang
%A Gangfang Xu
%A Baoan Song
%A Song Yang
%A Linhong Jin
%A Wei Xue
%A Deyu Hu
%A Ping Lu
%A Zhuo Chen
%J Molecules
%D 2006
%I MDPI AG
%R 10.3390/11060383
%X A simple, efficient, and general method has been developed for the synthesis ofvarious 3-alkylquinazolin-4-one derivatives from quinazolin-4-one treated with alkylbromides under phase transfer catalysis condition. The structures of the compounds werecharacterized by elemental analysis, IR, 1H-NMR and 13C-NMR spectra. Title compound6-bromo-3-propylquinazolin-4-one (3h) was found to possess good antifungal activity.
%K Quinazolinone
%K Phase Transfer Catalyst
%K synthesis
%K antifungal activity
%U http://www.mdpi.com/1420-3049/11/6/383