%0 Journal Article
%T One-Pot Quinazolin-4-yl-thiourea Synthesis via N-(2-Cyanophenyl) benzimidoyl isothiocyanate
%A W. Fathalla
%A M. £żajan
%A J. Marek
%A P. Pazdera
%J Molecules
%D 2001
%I MDPI AG
%R 10.3390/60700588
%X 1-substituted-3-(2-phenylquinazolin-4-yl) thioureas (7) were produced by an intramolecular cycloaddition reaction of 1-substitued-3-[(2-cyanophenylimino) phenylmethyl] thioureas (3). These compounds in turn were prepared by the reaction of N-(2-cyanophenyl)benzimidoyl isothiocyanate (2) with primary amines. The structures of products 7 were confirmed by FTIR, 1H-NMR, 13C-NMR, mass spectroscopy and X-ray crystallography.
%K 1-(2-phenylquinazolin-4-yl)-3-substituted thioureas
%K 1-[(2-cyanophenylimino) phenylmethyl]-3-substituted thioureas
%K N-(2-cyanophenyl)- benzimidoyl isothiocyanate
%K one-pot synthesis
%K amidinoyl isothiocyanates
%U http://www.mdpi.com/1420-3049/6/7/588