%0 Journal Article
%T Synthesis and Biological Activity of 3-(2-Furanyl)-6-Aryl-1,2,4-Triazolo[3,4-b]-1,3,4 ¨CThiadiazoles
%A Li-Xue Zhang
%A An-Jiang Zhang
%A Xian-Xing Chen
%A Xin-Xiang Lei
%A Xiang-Yun Nan
%A Dong-Yong Chen
%A Zi-Yi Zhang
%J Molecules
%D 2002
%I MDPI AG
%R 10.3390/70800681
%X 3-(2-Furanyl)-4-amino-5-mercapto-1,2,4-triazole (1) was prepared from 2-furoic acid through a multi-step reaction sequence. Compound 1 reacted with aromatic acids in the presence of phosphorus oxychloride to give 3-(2-furanyl)-6-aryl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles (2). The structures of all the newly synthesized compounds have been confirmed by elemental analysis, IR, 1H-NMR, 13C-NMR and mass spectra. The bioassay indicated most of the title compounds possess significant growth promoting effects on mung bean radicles.
%K Furan ring
%K triazolothiadiazoles
%K synthesis
%K spectral characterization
%K biological activity
%U http://www.mdpi.com/1420-3049/7/8/681