%0 Journal Article
%T Synthesis of 5,6-Dihydropyridin-2(1H)-ones, 1,5,6,8,8a-Hexahydroisoquinolin-3(2H)-ones and 4a,5,6,7,8,8a-Hexahydroquinolin-2(1H)-ones by Intramolecular Wittig Reaction
%A Alexander S. Fisyuk
%A Nikolai V. Poendaev
%J Molecules
%D 2002
%I MDPI AG
%R 10.3390/70200124
%X A new, universal and diastereospecific method has been developed for the synthesis of 5,6-dihydropyridin-2(1H)-ones, 1,5,6,8,8a-hexahydroisoquinolin-3(2H)-ones and 4a,5,6,7,8,8ahexahydroquinolin-2(1H)-ones (4) based on the intramolecular Wittig cyclization of the triphenyphosphonium salts 2 derived from the N-(3-oxoalkyl)¨Cchloroacetamides 1.
%K 5
%K 6-dihydropyridin-2(1H)-one
%K Wittig reaction
%K intramolecular cyclization
%K N-(3- oxoalkyl)chloroacetamide
%U http://www.mdpi.com/1420-3049/7/2/124