%0 Journal Article
%T Thermal Rearrangement of Allyl Substituted Unsymmetric 4H-1,2,4-Triazoles to the Corresponding 1H-1,2,4-triazoles
%A K£¿re B. J£¿rgensen
%A Ragnhild B. Olsen
%A Per H.J. Carlsen
%J Molecules
%D 2001
%I MDPI AG
%R 10.3390/60500481
%X A series of neat 4-(2-alkenyl) substituted 5-methyl-3-phenyl-4H-1,2,4-triazoles were thermolyzed at 320 oC producing a rearrangement products, of which the regioisomeric 1- and 2-substituted triazoles were the main products. The group migrations were rationalized in terms of consecutive SN2-type reactions. This mechanism was supported by a study of the alkylations of the triazoles which gave similar product mixtures. 4-(2-alkenyl) substituted 3-phenyl-4H-1,2,4-triazoles, on the other hand, gave predominantly elimination products.
%K Thermolysis
%K 1
%K 2
%K 4-triazole
%K rearrangement
%U http://www.mdpi.com/1420-3049/6/5/481