%0 Journal Article
%T Generation and Cycloaddition of o-Quinodimethane in Aqueous Medium
%A Lothar W. Bieber
%A Margarete F. Da Silva
%J Molecules
%D 2001
%I MDPI AG
%R 10.3390/60500472
%X o-Quinodimethane can be generated from =¦Á,¦Á'-dihalo-o-xylenes using zinc in aqueous solution. In the presence of activated dienophiles cycloadducts can be obtained directly. Catalysis with tris-triphenylphosphine ruthenium(II) dichloride reduces side reactions such as reduction and polymerisation and improves the yield. This is the first example of an organometallic cyclisation in aqueous medium using dihalo compounds.
%K Dehalogenation
%K zinc
%K Diels-Alder reaction
%K Ru catalysis
%K aqueous solvent
%U http://www.mdpi.com/1420-3049/6/5/472