%0 Journal Article
%T Some Anilides of 2-Alkylthio- and 2-Chloro-6-Alkylthio-4-Pyridinecarboxylic Acids: Synthesis and Photosynthesis-Inhibiting Activity
%A Miroslav Milet¨ªn
%A Martin Dole£¿al
%A Veronika Opletalov¨¢
%A Ji£¿¨ª Hartl
%A Katar¨ªna Kr¨¢l¡¯ov¨¢
%A Milo£¿ Mach¨¢£¿ek
%J Molecules
%D 2001
%I MDPI AG
%R 10.3390/60700603
%X Many compounds containing a -CONH- group display photosynthesis inhibiting activity. Based on this structural feature, a group of anilides of 2-alkylthio-(1b-4f) or 2-chloro-6-alkylthio-4-pyridinecarboxylic acids (5a-6c) was synthesised. The prepared compounds were tested for their inhibition of the oxygen evolution rate (OER) in spinach chloroplasts. A quasi-parabolic dependence between photosynthesis-inhibiting activity and the lipophilicity of the compounds was determined for 1b-4f as well as for 5a-6c. The inhibitory activity of compounds 1b-4f was higher than that of 5a-6c for comparable lipophilicity values.
%K 2-Alkylthio-4-pyridinecarboxylic acids
%K Anilides
%K Photosynthesis inhibition
%U http://www.mdpi.com/1420-3049/6/7/603