%0 Journal Article
%T Synthesis of 6-Nitroderivatives of Oxazolo[3,2-a]-pyridines and Their Reactions with Nucleophiles
%A Alexander A. Bush
%A Eugene V. Babaev
%J Molecules
%D 2003
%I MDPI AG
%R 10.3390/80600460
%X 5-Nitro-2-pyridone can be selectively N-phenacylated, and the resulting phenacylpyridones I undergo cyclization to 6-nitrooxazolo[3,2-a]pyridinium salts II. These salts II readily react with ammonia and aliphatic amines leading to the products of pyridine ring opening - previously unknown 1-amino-2-nitro-4-(oxazole-2-yl)butadienes-1,3. Reaction of salts II with water lead to hydrolytic cleavage of the oxazole fragment.
%K 5-Nitro-2-pyridone
%K oxazolo[3
%K 2-a]pyridine
%K butadiene
%K nitrodiene
%K aminodiene
%K oxazolyldiene
%U http://www.mdpi.com/1420-3049/8/6/460