%0 Journal Article
%T A New Convenient Synthesis of 5-Acyl-1,2,3,4-tetrahydropyrimidine-2-thiones/ones
%A Anatoly D. Shutalev
%A Ekaterina A. Kishko
%A Natalie V. Sivova
%A Aleksei Yu. Kuznetsov
%J Molecules
%D 1998
%I MDPI AG
%R 10.3390/30300100
%X An efficient one-pot synthesis of 5-acyl-1,2,3,4-tetrahydropyrimidine-2-thiones/ones is described. The synthesis is based on the reaction of readily available ¦Á-tosyl substituted thioureas or ureas with enolates of ¦Â-oxoesters or 1,3-dicarbonyl compounds followed by acid-catalyzed dehydration of the obtained 5-acyl-4-hydroxyhexahydropyrimidine-2-thiones/ones.
%K ¦Á-Tosyl substituted (thio)ureas
%K 5-acyl-1
%K 2
%K 3
%K 4-tetrahydropyrimidine-2-thiones/ones
%U http://www.mdpi.com/1420-3049/3/3/100