%0 Journal Article
%T Effect of Microwave Irradiation on the Condensation of 6-Substituted 3-Formylchromones with Some Five-membered Heterocyclic Compounds
%A Margita Lacova
%A Renata Gasparova
%A Dusan Loos
%A Tibor Liptay
%A Nada Pronayova
%J Molecules
%D 2000
%I MDPI AG
%R 10.3390/50200167
%X Different types of 3-substituted 4H-4-oxobenzopyrans were prepared by microwave irradiation as well as by a classical method. The beneficial effect of microwave irradiation on the aldol condensation of 3-formylchromones with 2-imino-1-methylimidazolidine-4-one (creatinine), 2-thioxoimidazolidine-4-one (thiohydantoin) and 2-ethyl-2-thioxothiazolidin-4-one (3-ethylrhodanine) in different reaction media is described. Our results show that the effect of microwave irradiation on the reactions studied was a shortening of the reaction times and a smooth increase in the yields. The subsequent reactions of the product with some nucleophiles are discussed. The structure of the products was proven by elemental analysis, IR and NMR spectra.
%K Creatinine
%K thiohydantoin
%K rhodanine
%K carbamoic acids
%K guanidine derivatives
%K Diels - Alder reaction
%K IR
%K 1H NMR
%K 13C NMR
%U http://www.mdpi.com/1420-3049/5/2/167