%0 Journal Article
%T 4-[5-(3,5-Difluorophenyl)furan-2-yl]-2,3,7-triazaspiro[4.5]dec-3-en-1-one Hydrochloride
%A Rajagopalan Srinivasan
%A Badiadka Narayana
%A Seranthimata Samshuddin
%A Balladka Kunhanna Sarojini
%J Molbank
%D 2012
%I MDPI AG
%R 10.3390/M773
%X A novel route for the synthesis of new spirocyclic derivative is developed. The present work involves the synthesis of title compound 3 by Suzuki coupling of 3,5-difluorophenyl boronic acid with tert-butyl 1-(5-bromofuran-2-yl)-4-oxo-2,3,7-triazaspiro[4.5]dec-1-ene-7-carboxylate ( 2), which in turn prepared from the ethyl nipecotate ( 1). Newly prepared spirocyclic derivative ( 3) is characterized by IR, NMR and mass spectral data.
%K spirocyclic
%K pyrazolone
%K Suzuki coupling
%K ethyl nipecotate
%U http://www.mdpi.com/1422-8599/2012/3/M773