%0 Journal Article
%T Novel Coumarin Derivatives with Expected Biological Activity
%A Z. M. Nofal
%A M. I. El-Zahar
%A S. S. Abd El-Karim
%J Molecules
%D 2000
%I MDPI AG
%R 10.3390/50200099
%X A number of novel 3-bromo-4-methyl-7-methoxy-8-amino substituted coumarins and 2-substituted 7-bromo-6-methyl-8H-pyrano-benzimidazoles, benzoxazoles and/or benzoxazine-8-ones were synthesized for the purpose of pharmacological evaluation. Some representative compounds showed antitumor activity in vitro on Ehrlich ascites carcinoma in the preliminary testing.
%K Substituted coumarins
%K nitro reduction
%K benzylidinyl amino coumarins
%U http://www.mdpi.com/1420-3049/5/2/99