%0 Journal Article
%T A High-Yielding Synthesis of the Naturally Occurring Antitumour Agent Irisquinone
%A John A. Hadfield
%A Alan T. McGown
%A John Butler
%J Molecules
%D 2000
%I MDPI AG
%R 10.3390/50100082
%X A short, high-yielding synthesis of the antitumour agent irisquinone (1) is described. The key steps are the palladium catalysed coupling reaction of dec-9-yn-1-ol with iodide (2) to form alkyne (3) and the Fremy¡¯s salt oxidation of phenol (7).
%K Irisquinone
%K antitumour
%K Chinese medicine
%U http://www.mdpi.com/1420-3049/5/1/82