%0 Journal Article
%T Design and Synthesis of a Conformationally Rigid Mimic of the Dihydropyrimidine Calcium Channel Modulator SQ 32,926
%A Birgit Jauk
%A Tetiana Pernat
%A C. Oliver Kappe
%J Molecules
%D 2000
%I MDPI AG
%R 10.3390/50300227
%X A conformationally rigid polyheterocycle (3) which mimics the putative receptorbound conformation of dihydropyridine-type calcium channel modulators is prepared in a seven-step reaction sequence based on a Biginelli-type cyclocondensation reaction.
%K Dihydropyrimidines
%K Biginelli reaction
%K isom¨šnchnones
%K 1
%K 3-dipolar cycloaddition reactions
%K AM1 calculations
%K conformation
%U http://www.mdpi.com/1420-3049/5/3/227