%0 Journal Article
%T STUDIES ON FOURIER TRANSFORM IR SPECTRA OF HUMAN MYELOCYTIC LEUKEMIA XENOGRAFTED IN NUDE MICE<br>人早幼粒白血病细胞裸鼠异种移植模型的傅里叶变换红外光谱探索
%A TANG Wei-Yue
%A SUN Lei-Ming
%A HOU Xiao-Qiang
%A CHEN Xiang-Cai
%A Zhang Jian-Min
%A <br>唐伟跃
%A 孙雷明
%A 侯晓强
%A 陈香才
%A 张建民
%J 红外与毫米波学报
%D 2006
%I Science Press
%X Fourier transform infrared spectroscopy(FTIR) was applied to the study of human myelocytic leukemia(HL-60) xenografted in nude mice.Experiment results show that(1) the peak of CH_3 and C-O of molecule of protein shifts to a certain extent in cancerous tissues,(2) the relative intensity of 1746cm~(-1) is very strong in normal tissues,but it is very weak in malignant tissues,(3) the relative intensity of the stretch vibration of PO_2~-in phosphodiester group is obviously strong,(4) the ratio of the relative intensity of deformed vibration of the adipose molecule and the deoxyribose vibration of CH_3 was higher in normal tissues,but it is almost equal in malignant tissues.The result might indicate that the FTIR could be used in the clinical diagnoses of the malignant tissues of human myelocytic leukemia(HL-60) xenografted in nude mice,and it also suggests that the nude mice tumor models could be a new method for the FTIR spectroscopic studies of tumor.
%K nude mice
%K HL-60
%K tumor
%K infrared spectra<br>裸鼠
%K 人早幼粒白血病细胞
%K 肿瘤组织
%K 红外光谱
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=5B3AB970F71A803DEACDC0559115BFCF0A068CD97DD29835&cid=1319827C0C74AAE8D654BEA21B7F54D3&jid=D3B4F771D1A06062008B4D0A2EF05996&aid=D443E8C2DA6C51CE&yid=37904DC365DD7266&vid=C5154311167311FE&iid=E158A972A605785F&sid=69E4C201C13601F9&eid=C1B34927D429E92F&journal_id=1001-9014&journal_name=红外与毫米波学报&referenced_num=0&reference_num=7