%0 Journal Article
%T The research on pathogenicity of fish nervous necrosis virus to Rachycentron canadum juvenile<br>鱼类神经坏死病毒对军曹鱼仔鱼的致病性
%A YAN Yun-feng
%A SU You-lu
%A GUO Zhi-xun
%A XU Li-wen
%A FENG Juan
%A HUANG Jian-nan
%A YU Da-hui
%A <br>闫云锋
%A 苏友禄
%A 郭志勋
%A 徐力文
%A 冯娟
%A 黄剑南
%A 喻达辉
%J 海洋科学
%D 2010
%I 
%X In this paper, the pathogenicity of fish nervous necrosis virus to Rachycentron canadum juveniles was studied by observations of the mortality and histo-pathological changes through three infected routes including intramuscular injection (IM), bath exposure and cohabitation. The results showed that the juveniles infected with NNV manifested the typical symptom such as severe sickness with anorexia, pale-grey pigmentation of body and whirling swimming. And the cumulative mortalities of infected fish via IM injection, bath exposure infection and cohabitation were 78%, 44% and 34%, respectively. NNV could be detected in the brain, eye and spinal cord of the infected R. canadum juveniles with RT-PCR at 18h post-IM injection. Microscopic observation revealed vacuolations in brain, retina and spinal cord of the infected juveniles. So the results demonstrated that R. canadum juveniles were susceptible to nervous necrosis virus and the virus could transmit horizontally among the juveniles by water.
%K fish nervous necrosis virus
%K Rachycentron canadum juvenile
%K pathogenicity<br>鱼类神经坏死病毒
%K 军曹鱼(Rachycentron
%K )仔鱼
%K 致病性
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=E62459D214FD64A3C8082E4ED1ABABED5711027BBBDDD35B&cid=2D9C75573FA3E416&jid=DFE7B94EB76B8F26135C9890832CEF6A&aid=6FD46F42FC354EA89E30913002A27F02&yid=140ECF96957D60B2&vid=339D79302DF62549&iid=E158A972A605785F&sid=B31275AF3241DB2D&eid=F3090AE9B60B7ED1&journal_id=1000-3096&journal_name=海洋科学&referenced_num=0&reference_num=16