%0 Journal Article
%T Effects of cadmium on antioxidant enzyme activities and lipid peroxidation in the mantle and gill of the freshwater bivalve A. woodiana woodiana<br>镉对背角无齿蚌外套膜和鳃抗氧化酶活性及脂质过氧化的影响
%A XING Huifang
%A LI Yongquan
%A YANG Huizhen
%A WANG Lan
%A <br>邢慧芳
%A 李涌泉
%A 杨慧珍
%A 王兰
%J 环境科学学报
%D 2013
%I 
%X To explore the effects of cadmium on antioxidant enzymes activities and lipid peroxidation in the mantle and gill of the freshwater bivalve A. woodiana woodiana, according to LC50 of 134.9 mg·L-1 at the 96th hour, bivalves were exposed to different concentrations of cadmium (4.22, 8.43, 16.82, 33.7 and 67.45 mg·L-1) for 24, 48, 72 and 96 hours. Activities of superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT) and the contents of malondialdehyde (MDA) were determined with the mantle and gill of the treated bivalves. Changes in activities of antioxidant enzymes from the mantle exhibited a pattern of inhibition-induction-inhibition while branchial enzymatic activities were initially induction, followed by inhibition with increasing Cd concentration. The induction of enzymatic activities following the Cd treatment appeared to be tissue-specific, with the induction of branchial enzymatic activities occurring earlier than that for the mantle. The contents of MDA were found to continuously increase in both the mantle and the gill. Our results also showed a significant increase (**p<0.01) in lipid peroxidation in the mantle and gill after treatment with a high concentration of cadmium, indicating a concentration-dependent and time-dependent manner.
%K A
%K woodiana woodiana
%K mantle and gill
%K antioxidant enzyme
%K lipid peroxidation
%K cadmium<br>背角无齿蚌
%K 外套膜和鳃
%K 抗氧化酶
%K 脂质过氧化
%K 镉
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=03A55E61A8750ACAC6AF81EF9E2AC838&aid=523711B464E4FFDF9CC53A0FF514E161&yid=FF7AA908D58E97FA&vid=27746BCEEE58E9DC&iid=38B194292C032A66&sid=353B961D86F026C0&eid=E9F71A2A3584AD5D&journal_id=0253-2468&journal_name=环境科学学报&referenced_num=0&reference_num=19