%0 Journal Article
%T The toxic effects of methylmercury on undifferentiated PC12 cells<br>甲基汞对未分化型PC12细胞的毒性机制
%A ZHANG Peng
%A XU Yongping
%A LI Xiaoyu
%A JIN Liji
%A <br>张鹏
%A 徐永平
%A 李晓宇
%A 金礼吉
%J 环境科学学报
%D 2009
%I 
%X Undifferentiated PC12 cells were used as an in vitro model to study the toxicity of methylmercury toward dopaminergic neurons.Methylmercury-induced cytotoxicity was detected by MTT assay.The morphological changes were observed by Hoechst33258 staining.The number of cells in different parts of the cell cycle and the rate of apoptosis were analysed quantitatively by flow cytometry.Further,various oxidative stress indicators were assessed by means of colorimetry.The results showed that methylmercury decreased ...
%K methylmercury
%K apoptosis
%K oxidative stress
%K undifferentiated PC12 cells<br>甲基汞
%K 细胞凋亡
%K 氧化应激
%K 未分化型PC12细胞
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=03A55E61A8750ACAC6AF81EF9E2AC838&aid=AAE5DFFF18F773F440CB6028FC640DE6&yid=DE12191FBD62783C&vid=771469D9D58C34FF&iid=B31275AF3241DB2D&sid=55C36125E841856F&eid=B593C98A8D813A42&journal_id=0253-2468&journal_name=环境科学学报&referenced_num=0&reference_num=14