%0 Journal Article
%T Effects of low-dose and long-term lead (Pb) exposure on testicular enzymes in male Rana nigromaculata<br>低剂量长期铅暴露对雄性黑斑蛙精巢组织关键酶活性的影响
%A WANG Meizhen
%A JIA Xiuying
%A <br>汪美贞
%A 贾秀英
%J 环境科学学报
%D 2012
%I 
%X To evaluate the reproductive toxicity of low-dose and long-term lead(Pb) exposure in male Rana nigromaculata,healthy adult male frogs were exposed to 0.1,0.2,0.4,0.8 and 1.6 mg · L-1 of lead solution for 30 d under experimental conditions.The activities of Ca2+-ATPase,Na+-K+-ATPase,Ca2+-Mg2+-ATPase,β-DG,LDH and ACP were tested.The results showed that the activities of Ca2+-ATPase and Na+-K+-ATPase were induced with the increasing lead level,while Ca2+-Mg2+-ATPase being inhibited.When the decrease of Ca2+-Mg2+-ATPase exceeded the increase of Ca2+-ATPase and Na+-K+-ATPase,the quantity of sperm decreased and the male reproductive toxicity of the frog was induced by lead.In addition,the activities of ACP were inhibited under 1.6 mg · L-1 Pb2+,implying decrease of the quantity of sperm because of damage of sertoli cell.Also,the activities of LDH were significantly inhibited under 0.4 mg · L-1 Pb2+,implying decrease of the quality of sperm because of the damage of spermatogenic cells.
%K lead
%K testes
%K reproductive toxicity
%K Rana nigromaculata<br>铅
%K 精巢
%K 生殖毒性
%K 黑斑蛙
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=03A55E61A8750ACAC6AF81EF9E2AC838&aid=F950C016BC33E9015F393FC19BD0E81A&yid=99E9153A83D4CB11&vid=9971A5E270697F23&iid=38B194292C032A66&sid=8A6D8366EA57F0FF&eid=895BB10EB8F3BD49&journal_id=0253-2468&journal_name=环境科学学报&referenced_num=1&reference_num=29