%0 Journal Article
%T IN VITRO METABOLISM OF ENVIRONMENTAL CARCINOGEN 2-NITRO-FLUORENE BY RAT LIVER S-9FRACTION<br>2－硝基芴大鼠肝微粒体体外代谢研究
%A Shen Jianwei
%A Wang Hai
%A Xu Xiaobai
%A <br>沈建伟
%A 王海
%A 徐晓白
%J 环境科学学报
%D 1995
%I 
%X In vitro metabolism of 2-nitro-fluorene by Aroclor 1254 induced rat liver micro somehas been investigated under ambient atmospheric condition.The metabolites have been iso-lated by reversed phase HPLC and identified by MS,UV,IR,HPLC and GC. Monohy-droxy 1-2-fluorenes and dihydroxy 1-2-nitro-fluorene are found at first time in metabolismproducts of 2-nitro-fluorene.Some minor products remained unidentified because of insuffi-cient quantities. The results of this study also confirm the complexity of the metabolic acti-vation pathways of nitro-polycyclic aromatic hydrocarbons.
%K Nitrofluorene mutagenicity
%K metabolism<br>硝基芴
%K 致突变性
%K 代谢
%K 大鼠
%K 肝
%K 微粒体
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=03A55E61A8750ACAC6AF81EF9E2AC838&aid=565942E7D3038E5EA76AB2E0D3D1282E&yid=BBCD5003575B2B5F&vid=23CCDDCD68FFCC2F&iid=0B39A22176CE99FB&sid=F9F74EC1AA08A7B9&eid=E089FDF3CDAE8561&journal_id=0253-2468&journal_name=环境科学学报&referenced_num=1&reference_num=3