%0 Journal Article %T Cellular and biochemical response in BALF of rats exposed to different concentrations of SO2
二氧化硫对大鼠肺泡细胞和肺泡灌洗液的生化效应 %A DU Qingping %A MENG Ziqiang %A
杜青平 %A 孟紫强 %J 环境科学学报 %D 2003 %I %X The Bronchoalveolar lavage cells(BALF) and the biochemical indexes in BALF were studied in the rats exposed to different concentrations of sulfur dioxide(SO_2).The results showed the numbers of alveolar macrophage were increased but its percentage decreased;Both the numbers and percentages of the neutrophils and lymphocytes increased in BALF,and they showed dose-response relationship.The pH values decreased significantly;the protein contents in BALF,the pulmonary vascular permeability index,the activities of acid phosphatase,alkaline phosphatase and Lactic dehydrogenase in BALF increased as well as the malondialdehyde contents.These cellular and biochemical indexes suggested different ways of damage of the structure and function of lung tissues and the cells. %K bronchoalveolar lavage fluid %K acid phosphatase %K alkaline phosphatase %K lactic dehydrogenase %K membrane permeability %K alveolar macrophages
二氧化硫 %K 大鼠 %K 肺泡细胞 %K 肺泡灌洗液 %K 生化效应 %K 生化指标 %K 酸性磷酸酶 %K 碱性磷酸酶 %K 乳酸脱氢酶 %K 膜通透性 %K 肺泡巨噬细胞 %K 毒性 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=03A55E61A8750ACAC6AF81EF9E2AC838&aid=68678F7D61BEE982&yid=D43C4A19B2EE3C0A&vid=EA389574707BDED3&iid=B31275AF3241DB2D&sid=E0FF0FB27B45F84E&eid=CE16DE2ABCD4D365&journal_id=0253-2468&journal_name=环境科学学报&referenced_num=4&reference_num=7