%0 Journal Article
%T STUDIES ON METABOLISM OF 2-NAPHTHYLAMINE AND ITS ACTIVATION MECHANISM<br>2-萘胺的代谢及其活化机理的研究
%A Li Tingshu
%A Dai Tianyou
%A Dai Qianhuan
%A Pei Shu
%A <br>李廷书
%A 戴天有
%A 戴乾圆
%A 裴淑
%J 环境科学学报
%D 1990
%I 
%X After incubation of 2-naphthylamine with induced rat liver microsome S9 preparation,the metabolites were isolated by using HPLC and identified as 2-amino8-naphthol(52.6%), 2-amino-5-naphthol(28.5%), 2-amino-6-naphthol(14.0%)and 2-amino-7-naphthol(4.9%). The measured results are same as those calculated by quantitative HMO based on Di-region theory. Both amino group and carbon atoms on the extra-ring play duality roles of activation and detoxification in metabolism.
%K 2-naphthylamine
%K metabolism
%K 2-aminonaphthols
%K Di-region theory<br>2－萘胺
%K 代谢
%K 活化
%K 双区理论
%K 污染物
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=03A55E61A8750ACAC6AF81EF9E2AC838&aid=4080D20520701876145A30EF181C8549&yid=8D39DA2CB9F38FD0&vid=F3090AE9B60B7ED1&iid=E158A972A605785F&sid=238BD7580EFCC5AE&eid=DA74B62FE4348759&journal_id=0253-2468&journal_name=环境科学学报&referenced_num=0&reference_num=3