%0 Journal Article
%T A COMPARATIVE STUDY ON CARCINOGENIC ACTIVITIES OF PBNA AND ITS ISOMER PANA IN ICR MICE<br>PBNA及其同分异构体PANA在小鼠ICR系中致癌性的比较研究
%A Wang D
%A Zeng Ruowang
%A Wang Hengwen
%A <br>王达
%A 曾若望
%A 王蘅文
%J 环境科学学报
%D 1983
%I 
%X Repeated subcutaneous injection of technical PBNA, technical PANA and chemically pure PANA in DMSO solution into young adult male ICR mice induced malignant tumors 34.6%, 46.6% and 52.2%, respectively at the end of IQth experimental month with a total dose of 432mg given to each animal. No malignant tumors appeared in controls using DMSO. PANA seemed to show dose-response relationship in tumor initiation. Both tend to induce pulmonary carcinomas, with PANA also to induce carcinomas and hemangio-endotheliomas of kidneys.
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=03A55E61A8750ACAC6AF81EF9E2AC838&aid=8AD768AF377407D80569C1317324B5C4&yid=A7F20A391020FDEE&vid=38B194292C032A66&iid=38B194292C032A66&sid=4290346F7268639E&eid=4D7D059FFBF006B9&journal_id=0253-2468&journal_name=环境科学学报&referenced_num=0&reference_num=0