%0 Journal Article
%T Oxidative Damages of Long-term Exposure to Low Level Fullerenes (C60) in Carassius auratus<br>人工纳米材料富勒烯(C60)低剂量长期暴露对鲫鱼的氧化伤害
%A ZHU Xiao-shan
%A ZHU Lin
%A LANG Yu-peng
%A LI Yan
%A DUAN Zheng-hua
%A YAO Kun
%A <br>朱小山
%A 朱琳
%A 郎宇鹏
%A 李燕
%A 端正花
%A 姚琨
%J 环境科学
%D 2008
%I 
%X To determine the potential effects of fullerenes (C60) on aquatic organism, larval Carassius auratus was exposed to low level C60 (0.04-1.0 mg x L(-1)) for 32 days. Then the oxidative damages in brain, liver and gill tissue of larval Carassius auratus were measured. The results showed that: compared to the control, the reduced glutathione (GSH) contents in all different tissues decreased significantly (p < 0.05), and the most serious inhibition of GSH with a 14.3% inhibition rate was found in the gill tissue of larval crucian exposed to 1 mg x L(-1) C60 aqueous suspension; whereas the superoxide dismutase (SOD) and catalase (CAT) activities in liver tissue, Na+ -K+ -ATPase activities in gill tissue were stimulated significantly (p < 0.05), and the maximal activity of them were 121.34% (exposed to 0.04 mg x L(-1) C60 aqueous suspension), 114.80% (exposed to 0.04 mg x L(-1) C60 aqueous suspension) and 348.59% (exposed to 0.20 mg x L(-1) C60 aqueous suspension) respectively than that of control. The experiment results indicated that oxidative damages induced by long-term exposure might play a role in the bio-toxicity of C60 to larval crucian.
%K nanomaterials
%K fullerene C60
%K Carassius auratus
%K exposure
%K ecotoxicity
%K oxidative damages<br>纳米材料
%K 富勒烯
%K 鲫鱼
%K 暴露
%K 生态毒性
%K 氧化伤害
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=64CD0AA99DD39F69401C615B85F123EF&aid=4BD2DCB99D195F6E3BD840C33507620F&yid=67289AFF6305E306&vid=771469D9D58C34FF&iid=E158A972A605785F&sid=466EAEA150F7AE77&eid=0B757E9DCA0EC579&journal_id=0250-3301&journal_name=环境科学&referenced_num=5&reference_num=18