%0 Journal Article
%T Five New Diterpenoids from an Okinawan Soft Coral, Cespitularia sp.
%A Prodip K. Roy
%A Wilmar Maarisit
%A Michael C. Roy
%A Junsei Taira
%A Katsuhiro Ueda
%J Marine Drugs
%D 2012
%I MDPI AG
%R 10.3390/md10122741
%X Five new diterpenoids 1¨C 5 were isolated from an Okinawan soft coral, Cespitularia sp., together with the known diterpenoid, alcyonolide ( 6). New diterpenoid structures were elucidated by spectroscopic methods and by comparison of their NMR data with those of related compounds. Alcyonolide ( 6) was cytotoxic against HCT 116 cells (IC 50 5.85 ¦ÌM), while these new diterpenoids 1¨C 5 were much less active (IC 50 28.2¨C91.4 ¦ÌM).
%K Cespitularia
%K cytotoxicity
%K diterpenoid
%K HCT 116 cells
%K alcyonolide
%U http://www.mdpi.com/1660-3397/10/12/2741