%0 Journal Article
%T Effect of Chlorimethylmercury on the Expression of c-fos and c-jun Genes in Rat Brain<br>氯化甲基汞对大鼠脑c-fos和c-jun基因表达的影响
%A Cheng Jinping
%A Wang Wenhua
%A Jia Jinping
%A <br>程金平
%A 王文华
%A 贾金平
%J 环境科学
%D 2003
%I 
%X To study the role of immediate early genes (IEG) c-fos and c-jun in the neurotoxic mechanism of methylmercury chloride(MMC), expression of FOS and JUN in rat brains was observed by using immuohistochemical methods. In the test group MMC (5.0mg/kg and 0.1mg/kg ) was injected into rats while in the control group normal saline was injected. The results showed that after rats exposed for 3 hours, the expression of FOS and JUN in brains was higher than those of the control rats, the results indicated that IEG could participate in the neurological toxicity induced by chlorimethylmercury.
%K methylmercury chloride
%K c-fos
%K c-jun
%K gene expression<br>氯化甲基汞
%K c-fos
%K c-jun
%K 基因表达
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=3FF3ABA7486768130C3FF830376F43B398E0C97F0FF2DD53&cid=A7CA601309F5FED03C078BCE383971DC&jid=64CD0AA99DD39F69401C615B85F123EF&aid=0781D581206B1E81&yid=D43C4A19B2EE3C0A&vid=B91E8C6D6FE990DB&iid=CA4FD0336C81A37A&sid=286FB2D22CF8D013&eid=014B591DF029732F&journal_id=0250-3301&journal_name=环境科学&referenced_num=10&reference_num=14