%0 Journal Article
%T Briarenolides F and G, New Briarane Diterpenoids from a Briareum sp. Octocoral
%A Pei-Han Hong
%A Yin-Di Su
%A Jui-Hsin Su
%A Yung-Husan Chen
%A Tsong-Long Hwang
%A Ching-Feng Weng
%A Chia-Hung Lee
%A Zhi-Hong Wen
%A Jyh-Horng Sheu
%A Nai-Cheng Lin
%A Yueh-Hsiung Kuo
%A Ping-Jyun Sung
%J Marine Drugs
%D 2012
%I MDPI AG
%R 10.3390/md10051156
%X Two new briarane diterpenoids, briarenolides, F ( 1) and G ( 2), were isolated from an octocoral identified as Briareum sp. The structures of briaranes 1 and 2 were established by spectroscopic methods and by comparison of the spectroscopic data with those of known briarane analogues. Briarenolide F was proven to be the first 6-hydroperoxybriarane derivative and this compound displayed a significant inhibitory effect on the generation of superoxide anion by human neutrophils.
%K briarenolide
%K briarane
%K Briareum
%K superoxide anion
%U http://www.mdpi.com/1660-3397/10/5/1156