%0 Journal Article
%T Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum
%A Wenhui Wu
%A Keiji Hasumi
%A Hui Peng
%A Xianwen Hu
%A Xichang Wang
%A Bin Bao
%J Marine Drugs
%D 2009
%I MDPI AG
%R 10.3390/md7020085
%X Two of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy. The two compounds were identified to be 1-O-palmitoyl-2-O-oleoyl-3-O-(¦Á-D-glucopyranosyl) ¨Cglycerol (POGG) and 1-O-myristoyl-2-O-oleoyl-3-O-(¦Á-D-glucopyranosyl) ¨C glycerol (MOGG) which were obtained from Sargassum fulvellum for the first time. POGG and MOGG showed fibrinolytic activity in the reaction system of pro-u-PA and plasminogen.
%K fibrinolytic activity
%K NMR
%K glucopyranosyldiacylglycerol
%K structure determination
%K Sargassum fulvellum
%U http://www.mdpi.com/1660-3397/7/2/85